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Artifact-Compensated Time-Continuous Recording from Neural Tissue during Stimulation Using a Capacitively Coupled In-Vitro CMOS-MEA with 4k Recording and 1k Stimulation Sites
Zitatschlüssel Articale_Bertotti_2016_10
Autor G. Bertotti, J. Florian, N. Dodel, St. Keil, C. Boucsein, A. Möller, K. Boven, G. Zeck, and R. Thewes
Buchtitel IEEE Biomedical Circuits and Systems Conference (BioCAS)
Seiten pp. 303-306
Jahr 2016
DOI 10.1109/BioCAS.2016.7833780
Jahrgang IEEE Biomedical Circuits and Systems Conference (BioCAS)
Zusammenfassung A CMOS MEA with 4k recording and 1k stimulation sites is used for time-continuous recording of neural signals during stimulation. All sites consist of thin metal electrodes on the chip surface covered by a thin high-k dielectric. Recording and stimulation channels are electrically separated but physically superimposed so that recording at the site of stimulation is possible as well as at any other location within the array. A compensation method is introduced to fully compensate for stimulation signal-induced artifacts in the recording channels. Measurement results reveal the feasibility of our approach.
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